2-(Methylthio)-5-(phenylthio)pyrimidine-4-carboxylic acid CAS 61727-07-9
| CAS No. | 61727-07-9 |
| Molecular Formula | C12H10N2O2S2 |
| Molecular Weight | 278.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Methylthio)-5-(phenylthio)pyrimidine-4-carboxylic acid (CAS 61727-07-9), a certified reference material (molecular formula C12H10N2O2S2, MW 278.35 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Methylthio)-5-(phenylthio)pyrimidine-4-carboxylic acid (C12H10N2O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10N2O2S2 |
| Molecular Weight | 278.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Methylthio Standards
- 3-(Methylthio)-2-phenyl-2,4-dihydroindeno[1,2-c]pyrazole (CAS 871110-06-4)
- 6-(2-(Methylthio)ethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine (CAS 920503-55-5)
- 3,3'-Bis(methylthio)-[1,1'-biphenyl]-4,4'-diol (CAS 197148-67-7)
- 3-Methyl-2-(methylthio)-5-nitro-6-(pyridin-4-yl)pyrimidin-4(3H)-one (CAS 831231-60-8)
- 4-(Methylthio)-2-thioxo-3-(p-tolyl)-2,3-dihydrothiazole-5-carbonitrile (CAS 478261-56-2)
- 2-Methyl-3-(methylthio)-4-(trifluoromethyl)-3,5-dihydro-1H-pyrrolo[3,4-c]pyridine-1,6(2H)-dione (CAS 1269533-32-5)
- 2-((6-(Methylthio)pyridin-3-yl)amino)-5-nitropyrimidin-4(1H)-one (CAS 77961-70-7)
- 2-(Methylthio)-4,6-diphenyl-1,3,5-triazine (CAS 735-69-3)
Recommended Standards
- 2-(Ethylsulfanyl)-1-methyl-1H-imidazole-5-carbaldehyde N-(4-fluorophenyl)hydrazone (CAS 477854-43-6)
- 2-(Pentan-2-yl)anthracene-9,10-dione (CAS 75931-61-2)
- 2-(4-(tert-Butyl)phenyl)quinazolin-4(1H)-one (CAS 59455-93-5)
- 2-(tert-Pentyl)anthracene-9,10-dione (CAS 32588-54-8)
- corianin (CAS 35481-77-7)
- Tungsten boride (WB) (CAS 12007-09-9)
- 2-(3-Chlorophenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine (CAS 1782655-75-7)
- (6-Phenylpyridin-2-yl)boronic acid (CAS 1218790-96-5)
- 2-(Bromomethyl)-4-chloropyridine (CAS 856850-18-5)
- Glutathione-diethyl ester (reduced) HCL (CAS 97451-40-6（free base）)
- 4-Bromopyridine-2-carbonitrile (CAS 62150-45-2)
- Fexofenadine Impurity 34 (CAS CATO-C4X-179434)
- 4-(2,5-Dioxopyrrolidin-1-yl)-N-(p-tolyl)benzenesulfonamide (CAS 331432-28-1)
- Liraglutide Impurity 15 TFA Salt (CAS CATO-C4X-199215)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com