4-((2,4-Difluorophenyl)amino)-4-oxobut-2-enoic acid CAS 198077-70-2
| CAS No. | 198077-70-2 |
| Molecular Formula | C10H7F2NO3 |
| Molecular Weight | 227.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-((2,4-Difluorophenyl)amino)-4-oxobut-2-enoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-((2,4-Difluorophenyl)amino)-4-oxobut-2-enoic acid (CAS 198077-70-2), molecular formula C10H7F2NO3 and molecular weight 227.16 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-((2,4-Difluorophenyl)amino)-4-oxobut-2-enoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 227.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H7F2NO3 |
| Molecular Weight | 227.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenyl Standards
- 5-(3,4-Difluorophenyl)-4,5-dihydro-1,2-oxazole-3-carboxylic acid (CAS 1018170-52-9)
- 3-(2,5-Difluorophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 1096348-81-0)
- (E)-4-((2,4-difluorophenyl)amino)-4-oxobut-2-enoic acid (CAS 1164538-71-9)
- 3-(3,5-Difluorophenyl)-4,5-dihydroisoxazole-5-carboxylic acid (CAS 1694094-73-9)
- (Z)-4-((2,4-difluorophenyl)amino)-4-oxobut-2-enoic acid (CAS 6954-64-9)
- 4-(3,4-Difluorophenyl)pyrrolidine-3-carboxylic acid (CAS 1342031-77-9)
- 4-(2,3-Difluorophenyl)pyrrolidine-3-carboxylic acid (CAS 1343575-62-1)
- (2,3-Difluorophenyl)(morpholino)methanone (CAS 351038-43-2)
Recommended Standards
- 3-(Dichloro(methyl)silyl)propyl acrylate (CAS 71550-63-5)
- 4-(Difluoromethoxy)-1h-indole-2-carboxylic acid (CAS 885524-95-8)
- 2,3,4,6-Tetrafluoro-5-phenylpyridine (CAS 29636-84-8)
- 4-Isopropyl-2-(1,1,2,2-tetrafluoroethyl)oxazol-5(2H)-one (CAS 51314-53-5)
- methyl 2-bromo-2-(4-cyanophenyl)acetate (CAS 885953-33-3)
- 1-N-(2,2,2-trifluoroethyl)benzene-1,2-diamine (CAS 1152594-19-8)
- (4-(4-Fluorophenyl)furan-2-yl)boronic acid (CAS 2096331-23-4)
- tert-Butyl (S)-1-(chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indole-3-carboxylate (CAS 130007-86-2)
- 4-(3-((tert-Butoxycarbonyl)amino)phenyl)butanoic acid (CAS 149505-99-7)
- 2-(2-Bromo-4-fluorophenoxy)acetic acid (CAS 399-40-6)
- 2-[3-(difluoromethoxy)phenyl]acetic acid (CAS 262587-06-4)
- 5-Chloro-2-(2-isopropylphenoxy)aniline (CAS 946715-10-2)
- Benzyl (S)-(4-amino-5-hydroxypentyl)carbamate hydrochloride (CAS 2191381-68-5)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com