Propofol EP Impurity J(Propofol Related Compound B) CAS 1988-11-0

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.1988-11-0
Molecular FormulaC12H16O2
Molecular Weight192.25 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Propofol EP Impurity J(Propofol Related Compound B) CAS 1988-11-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Propofol EP Impurity J(Propofol Related Compound B).

CATO supplies Propofol EP Impurity J(Propofol Related Compound B) (CAS 1988-11-0), a pharmacopoeial impurity reference standard (molecular formula C12H16O2, MW 192.25 g/mol) used for the identification and quantification of trace impurities in APIs.

Propofol EP Impurity J(Propofol Related Compound B) (C12H16O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Propofol EP Impurity J(Propofol Related Compound B) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H16O2
Molecular Weight192.25 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity>90%
StorageStore at 2-8°C
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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