Estradiol Hemihydrate EP Impurity A CAS 19973-76-3
| CAS No. | 19973-76-3 |
| Molecular Formula | C18H22O2 |
| Molecular Weight | 270.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Estradiol Hemihydrate EP Impurity A (C18H22O2) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Estradiol Hemihydrate EP Impurity A (CAS 19973-76-3), a certified reference material (molecular formula C18H22O2, MW 270.37 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Estradiol Hemihydrate EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22O2 |
| Molecular Weight | 270.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
Related Estradiol Standards
- Estradiol Impurity 2 (17beta-delta8,9-Dehydroestradiol) (CAS 23392-52-1)
- Estradiol EP Impurity D (CAS 791-69-5)
- Estradiol Impurity 21 (CAS 1187829-63-5)
- Estradiol Impurity 34 (CAS 3563-27-7)
- Estradiol Impurity 7 (CAS 7291-41-0)
- Estradiol Valerate Impurity 14 (CAS 57605-52-4)
- Estradiol Valerate Impurity 15 (CAS 55448-91-4)
- Estradiol Valerate Impurity 16 (CAS 57605-50-2)
Recommended Standards
- Dienogest Impurity 6 (CAS 2503-06-2)
- Cyclopropane-1,1,2-triyltribenzene (CAS 896-65-1)
- N-((2,3,4,9-Tetrahydro-1H-carbazol-6-yl)methyl)isobutyramide (CAS 852137-97-4)
- Cyclobutyl(spiro[indoline-3,4'-piperidin]-1'-yl)methanone (CAS 858347-69-0)
- 4-(Chloromethyl)-2-(4-chlorophenyl)-5-methyl-1,3-oxazole (CAS 832076-92-3)
- 1-Methoxy-4-((4-((1s,4r)-4-propylcyclohexyl)phenyl)ethynyl)benzene (CAS 116903-47-0)
- 2-((3-(Trifluoromethyl)pyridin-2-yl)oxy)ethan-1-amine (CAS 1248755-00-1)
- Ethyl 5-oxo-5-(pyridin-3-yl)pentanoate (CAS 22971-47-7)
- 2-(5-Methyl-7-oxo-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)acetic acid (CAS 842972-62-7)
- (4-(2-Fluoroethoxy)phenyl)methanamine (CAS 377735-26-7)
- Rosuvastatin EP Impurity G (Calcium Salt) (CAS 2414245-11-5)
- N-[(2-fluorophenyl)methyl]-2,3-dihydro-1H-inden-2-amine (CAS 610298-64-1)
- 2-(2-Pyrrolyl)ethylamine Hydrochloride (CAS 857418-70-3)
- Semaglutide impurity 69 (CAS CATO-C4X-222669)
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