Ethyl 3-(4-chlorophenyl)propiolate CAS 20026-96-4
| CAS No. | 20026-96-4 |
| Molecular Formula | C11H9ClO2 |
| Molecular Weight | 208.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ethyl 3-(4-chlorophenyl)propiolate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ethyl 3-(4-chlorophenyl)propiolate (CAS 20026-96-4) is a high-purity analytical reference standard with the molecular formula C11H9ClO2 and a molecular weight of 208.64 g/mol.
The molecular framework of Ethyl 3-(4-chlorophenyl)propiolate (C11H9ClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H9ClO2 |
| Molecular Weight | 208.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
Related Ethyl Standards
- (E)-2-(4-chlorophenyl)-3-(methoxyimino)propanenitrile (CAS 1013061-60-3)
- (5-(4-Chlorophenyl)isoxazol-3-yl)methanamine (CAS 1018662-18-4)
- 2-(4-Chlorophenyl)imidazole-5-methanol (CAS 1053657-17-2)
- 6-(4-Chlorophenyl)-4,5-dihydropyridazin-3(2H)-one (CAS 1079-73-8)
- N-((4-Chlorophenyl)(cyano)methyl)acetamide (CAS 110087-91-7)
- 1-(2-chlorophenyl)-3-prop-2-yn-1-ylurea (CAS 1197753-77-7)
- 2-(4-Chlorophenyl)-5-methyl-1H-pyrazol-3(2H)-one (CAS 13024-90-3)
- 4-(3-chlorophenyl)-3-methylisoxazol-5-amine (CAS 1311856-66-2)
Recommended Standards
- Ethyl 3-(3-chlorophenyl)prop-2-ynoate (CAS 58686-68-3)
- Linagliptin Impurity 51 (CAS 6640-59-1)
- Diethyl 2-chlorosuccinate (CAS 7209-04-3)
- N-(2-Chloro-4-methylphenyl)-2-cyanoacetamide (CAS 959387-06-5)
- 4-{[1,1'-biphenyl]-4-yl}-2-(3-fluoro-4-iodophenyl)pyrimidine (CAS 477870-86-3)
- Methyl 4-Fluoroindole-3-acetate (CAS 5159-06-8)
- 1-Methylazetidin-3-ol oxalate (CAS 2138100-38-4)
- Methyl 2-(2-cyanoethyl)-4,4-dimethyl-3-oxopentanoate (CAS 1384429-23-5)
- 4-(2,6-Difluorophenyl)piperidine (CAS 1019373-70-6)
- 1-(Methylsulfanyl)-3-oxocyclobutane-1-carboxylic acid (CAS 1481083-54-8)
- N-(4-(3-(4-Chlorophenyl)-3-oxoprop-1-en-1-yl)phenyl)acetamide (CAS 136835-01-3)
- Paliperidone Impurity 73 (CAS CATO-C4X-172473)
- Methyl 1-(1-methoxypropan-2-yl)-5-oxopyrrolidine-3-carboxylate (CAS 1355334-47-2)
- Neuropeptide S (human) (CAS 412938-67-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com