Sildenafil Impurity 294 CAS 200575-17-3
| CAS No. | 200575-17-3 |
| Molecular Formula | C10H11ClO5S |
| Molecular Weight | 278.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Sildenafil Impurity 294 (CAS 200575-17-3), a pharmacopoeial impurity reference standard (molecular formula C10H11ClO5S, MW 278.71 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Sildenafil Impurity 294 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 278.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Sildenafil Impurity 294 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO5S |
| Molecular Weight | 278.71 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Sildenafil Standards
- Sildenafil Impurity 28 (CAS 139756-26-6)
- Sildenafil Impurity 57 (CAS 200575-16-2)
- Sildenafil Impurity 308 (CAS CATO-C4X-1128308)
- Sildenafil Impurity 248 (CAS 139756-30-2)
- Sildenafil Impurity 71 (CAS 960009-35-2)
- Sildenafil Impurity 92 (CAS CATO-C4X-112892)
- Sildenafil Impurity 53 (CAS 2021224-02-0)
- Sildenafil Impurity 31 (CAS CATO-C4X-112831)
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