Sildenafil Impurity 57 CAS 200575-16-2
| CAS No. | 200575-16-2 |
| Molecular Formula | C9H9ClO5S |
| Molecular Weight | 264.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Sildenafil Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Sildenafil Impurity 57 (CAS 200575-16-2), a pharmacopoeial impurity reference standard (molecular formula C9H9ClO5S, MW 264.68 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Sildenafil Impurity 57 (C9H9ClO5S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H9ClO5S |
| Molecular Weight | 264.68 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Sildenafil Standards
- Sildenafil Impurity 308 (CAS CATO-C4X-1128308)
- Sildenafil Impurity 294 (CAS 200575-17-3)
- Sildenafil Impurity 53 (CAS 2021224-02-0)
- Sildenafil Impurity 28 (CAS 139756-26-6)
- Sildenafil Impurity SM2 (CAS 202066-14-6)
- Sildenafil Impurity 247 (CAS 360068-47-9)
- Sildenafil Impurity 248 (CAS 139756-30-2)
- Sildenafil Impurity 34 (CAS CATO-C4X-112834)
Recommended Standards
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- Lesinurad Impurity 11 (CAS CATO-C4X-147811)
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- Diclofenac Impurity 43 (CAS CATO-C4X-105143)
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- tert-Butyl 3,3-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate (CAS 2820191-55-5)
- Strontium bromide hexahydrate (CAS 7789-53-9)
- Liraglutide Sodium Salt (CAS 204656-20-2（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com