Propranolol Impurity 5 CAS 2007-72-9
| CAS No. | 2007-72-9 |
| Molecular Formula | C16H21NO2 |
| Molecular Weight | 259.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Propranolol Impurity 5 (CAS 2007-72-9) is a certified pharmaceutical impurity reference standard with the molecular formula C16H21NO2 and a molecular weight of 259.34 g/mol.
Propranolol Impurity 5 (C16H21NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H21NO2 |
| Molecular Weight | 259.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Propranolol Standards
- (S)-Propranolol, 98% (CAS 4199-09-1)
- Propranolol Impurity 30 (CAS 27827-19-6)
- Propranolol Impurity 31 (CAS CATO-C4X-151931)
- Propranolol Impurity 49 (CAS CATO-C4X-151949)
- Propranolol Impurity 52 (CAS CATO-C4X-151952)
- Propranolol Impurity 54 (CAS CATO-C4X-151954)
- Propranolol (CAS 525-66-6)
- Propranolol Impurity 15 (CAS CATO-C4X-151915)
Recommended Standards
- Amorolfine Impurity 37 (CAS CATO-C4X-154237)
- Atropine Impurity 46 (CAS 1690-22-8)
- Amorolfine Impurity 38 (CAS CATO-C4X-154238)
- Atropine Impurity 22 (CAS 16052-33-8)
- Empagliflozin Impurity 25 (CAS 915095-89-5)
- Lercanidipine Impurity 20 (CAS 890045-70-2)
- Flunarizine impurity 36 (CAS 57070-98-1)
- tert-Butyl 6-chloro-1h,2h,3h-pyrrolo[2,3-b]pyridine-1-carboxylate (CAS 679392-22-4)
- N-[(1R,2R)-2-Amino-1,2-bis(4-methoxyphenyl)ethyl]4-methylbenzenesulfonamide (CAS 852212-99-8)
- 2-((1H-indol-3-yl)thio)acetonitrile (CAS 61021-51-0)
- 875-99-0 beta-Pericyclocamphanone 4,7,7-Trimethyltricyclo(2.2.1.0(2,6))heptan-3-one Pericyclocamphanone (CAS 875-99-0)
- (S)-4-(((benzyloxy)carbonyl)amino)-5-(((S)-1-carboxy-2-phenylethyl)amino)-5-oxopentanoic acid (CAS 987-84-8)
- 6-Iodo-5-methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1228376-73-5)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com