Lercanidipine Impurity 20 CAS 890045-70-2
| CAS No. | 890045-70-2 |
| Molecular Formula | C20H23ClN2O6 |
| Molecular Weight | 422.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lercanidipine Impurity 20.
CATO supplies Lercanidipine Impurity 20 (CAS 890045-70-2), a pharmacopoeial impurity reference standard (molecular formula C20H23ClN2O6, MW 422.86 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Lercanidipine Impurity 20 (C20H23ClN2O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lercanidipine Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23ClN2O6 |
| Molecular Weight | 422.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Lercanidipine Standards
- Lercanidipine Impurity 22 (CAS CATO-C4X-136422)
- Lercanidipine Impurity 37 (CAS 75130-34-6)
- Lercanidipine Impurity 2 (CAS CATO-C4X-13642)
- Lercanidipine Impurity 54 (CAS CATO-C4X-136454)
- Lercanidipine Impurity 46 (CAS CATO-C4X-136446)
- Lercanidipine Impurity 58 (CAS CATO-C4X-136458)
- Lercanidipine Impurity 60 (CAS 100427-51-8)
- Lercanidipine Impurity 61 (CAS CATO-C4X-136461)
Recommended Standards
- Dapagliflozin Impurity 20 (CAS 2169998-23-4)
- Dapagliflozin Impurity 171 (CAS CATO-C4X-1138171)
- Ertugliflozin impurity 18 (CAS 1210344-55-0)
- Amlodipine Impurity 56 (CAS 2418591-36-1)
- Dotinurad Impurity 100 (CAS 723287-01-2)
- Nalmefene Impurity 25 (CAS CATO-C4X-126825)
- Tafluprost Impurity 2 (CAS CATO-C4X-21632)
- 3-(difluoromethoxy)benzohydrazide (CAS 321196-03-6)
- 1,3-Dioxolane-4-butanol, 2-ethenyl- (CAS 2421-08-1)
- 2-[(3-methylbut-2-en-1-yl)sulfanyl]-3-phenylpropanoic acid (CAS 1184144-84-0)
- Icaritin Impurity 8 (CAS 13620-31-0)
- 1-(5-Benzyl-4-phenyl-5-(piperidin-1-yl)-4,5-dihydro-1,3,4-thiadiazol-2-yl)ethanone (CAS 139617-46-2)
- Methyl 8-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline-4-carboxylate (CAS 1780803-68-0)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com