4-Hydroxy-5-iodo-2-methylbenzoic acid CAS 201810-63-1
| CAS No. | 201810-63-1 |
| Molecular Formula | C8H7IO3 |
| Molecular Weight | 278.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Hydroxy-5-iodo-2-methylbenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Hydroxy-5-iodo-2-methylbenzoic acid (CAS 201810-63-1) is a high-purity analytical reference standard with the molecular formula C8H7IO3 and a molecular weight of 278.04 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system, 4-Hydroxy-5-iodo-2-methylbenzoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 278.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7IO3 |
| Molecular Weight | 278.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | I-containing |
Related Hydroxy Standards
- 4-Hydroxy-3-iodo-5-methylbenzoic acid (CAS 1195666-68-2)
- Methyl 2-hydroxy-3-iodobenzoate (CAS 128033-28-3)
- 3-Hydroxy-2-iodo-4-methoxybenzaldehyde (CAS 138490-94-5)
- 2-(3-Hydroxy-5-iodophenyl)acetic acid (CAS 1393540-48-1)
- Methyl 4-Hydroxy-3-iodobenzoate (CAS 15126-06-4)
- 2-Hydroxy-3-iodo-4-methoxybenzaldehyde (CAS 155560-24-0)
- Methyl 3-Hydroxy-4-iodobenzoate (CAS 157942-12-6)
- 5-Hydroxy-2-iodo-4-methylbenzoic acid (CAS 1643953-27-8)
Recommended Standards
- 3-Iodo-5-methoxybenzoic acid (CAS 74440-82-7)
- 4-Iodo-2-methoxybenzoic acid (CAS 89942-34-7)
- 3-Iodo-4-methoxybenzoic Acid (CAS 68507-19-7)
- 4-Iodo-3-methoxybenzoic acid (CAS 282087-44-9)
- 2-Ethyl-2-(propoxymethyl)butane-1-sulfonyl chloride (CAS 1468678-17-2)
- 2-(2-Bromophenyl)-2-hydroxyacetic acid (CAS 7157-15-5)
- 1-Bromo-4-(4,4-difluorocyclohexyl)benzene (CAS 1897699-04-5)
- 2,4-Bis(decyloxy)benzoic acid (CAS 156447-87-9)
- Methyl 3-amino-5-(4-fluorobenzyl)picolinate (CAS 863443-05-4)
- 6-Bromo-7-fluoroquinolin-3-amine (CAS 2092836-06-9)
- D-erythro-Dihydrosphingosine-1-phosphate (CAS 28508-07-8)
- 4-[(tert-Butylamino)methyl]-2-methoxyphenol (CAS 498577-18-7)
- N-(2-Chlorophenyl)-2-hydrazinyl-5-nitrobenzene-1-sulfonamide (CAS 328028-43-9)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
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