2-Chloro-7-methoxyquinazolin-4(3H)-one CAS 20197-98-2

Purity 97%+In StockPharmaceutical Standards
CAS No.20197-98-2
Molecular FormulaC9H7ClN2O2
Molecular Weight210.62 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-7-methoxyquinazolin-4(3H)-one CAS 20197-98-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 210.62 g/mol gives 2-Chloro-7-methoxyquinazolin-4(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-Chloro-7-methoxyquinazolin-4(3H)-one (CAS 20197-98-2), a certified reference material (molecular formula C9H7ClN2O2, MW 210.62 g/mol) for analytical method development and quality control.

The molecular framework of 2-Chloro-7-methoxyquinazolin-4(3H)-one (C9H7ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Chloro-7-methoxyquinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H7ClN2O2
Molecular Weight210.62 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Halogen ContentCl-containing
Nitrogen Atoms2

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