Dexamethasone 21-Iodide CAS 2029-18-7
| CAS No. | 2029-18-7 |
| Molecular Formula | C22H28FIO4 |
| Molecular Weight | 502.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Dexamethasone 21-Iodide (CAS 2029-18-7) is a high-purity analytical reference standard with the molecular formula C22H28FIO4 and a molecular weight of 502.36 g/mol.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine/iodine substitution, Dexamethasone 21-Iodide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 502.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Dexamethasone 21-Iodide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H28FIO4 |
| Molecular Weight | 502.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/I-containing |
Related Dexamethasone Standards
- Dexamethasone Impurity 127 (CAS CATO-C4X-1165127)
- Dexamethasone Impurity 16 (CAS 55541-30-5)
- Dexamethasone Impurity 84 (CAS CATO-C4X-116584)
- Dexamethasone Impurity 87 (CAS CATO-C4X-116587)
- Dexamethasone Isonicotinate (CAS 2265-64-7)
- Dexamethasone Impurity 113 (CAS CATO-C4X-1165113)
- Dexamethasone Hemisuccinate (CAS 3800-86-0)
- Dexamethasone Impurity 114 (CAS CATO-C4X-1165114)
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