Ibrutinib Impurity 78 CAS 2031255-24-8
| CAS No. | 2031255-24-8 |
| Molecular Formula | C25H23N5O3 |
| Molecular Weight | 441.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ibrutinib Impurity 78 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Ibrutinib Impurity 78 (CAS 2031255-24-8) is a certified pharmaceutical impurity reference standard with the molecular formula C25H23N5O3 and a molecular weight of 441.48 g/mol.
Structurally, Ibrutinib Impurity 78 (C25H23N5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 441.48 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C25H23N5O3 |
| Molecular Weight | 441.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 5 |
Related Ibrutinib Standards
- Ibrutinib Impurity 170 (CAS CATO-C4X-1064170)
- Ibrutinib Racemate (CAS 936563-87-0)
- Ibrutinib (CAS 936563-96-1)
- Ibrutinib Impurity 1 (CAS 936563-97-2)
- Ibrutinib Impurity 20 (CAS 936563-92-7)
- Ibrutinib Impurity 40 (CAS CATO-C4X-106440)
- Ibrutinib Impurity 71 (CAS CATO-C4X-106471)
- Ibrutinib Impurity 2 (CAS 1839099-22-7)
Recommended Standards
- Azilsartan Impurity 187 (CAS CATO-C4X-1096187)
- NIP 142 (CAS 203002-58-8)
- Cefixime Impurity 73 (CAS CATO-C4X-113973)
- N-(3-(5-(4-Fluorophenyl)-1-(furan-2-carbonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide (CAS 865615-62-9)
- Pivmecillinam Impurity 12 (CAS CATO-C4X-232312)
- Cefdinir Impurity 81 (CAS 137171-77-8)
- Erdosteine Impurity 1 Sodium Salt(Mixture of Diastereomers) (CAS CATO-C4X-19631)
- [(2-fluorophenyl)sulfanyl]formonitrile (CAS 2605-31-4)
- 4-(2-Amino-1-(indolin-1-yl)ethyl)-N,N-dimethylaniline (CAS 954568-18-4)
- 1-((2-Chloropyridin-3-yl)methyl)azepane (CAS 1249151-66-3)
- 5-[(E)-2-(2,4-Difluorophenyl)diazen-1-yl]-2-(methylsulfanyl)pyrimidine-4,6-diol (CAS 339015-97-3)
- 2-[(4-methoxyphenyl)methoxy]pyridine-4-carboximidamide hydrochloride (CAS 1221726-29-9)
- 5-Bromo-2-methyl-1,2,3,4-tetrahydroisoquinoline (CAS 127693-22-5)
- D-[Ala]24-Semaglutide (CAS CATO-C4X-2226126)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com