Imatinib Impurity 67 CAS 2031255-25-9
| CAS No. | 2031255-25-9 |
| Molecular Formula | C25H24N6O3 |
| Molecular Weight | 456.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Imatinib Impurity 67 (C25H24N6O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Imatinib Impurity 67 (CAS 2031255-25-9, C25H24N6O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Imatinib Impurity 67 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H24N6O3 |
| Molecular Weight | 456.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 6 |
Related Imatinib Standards
- Imatinib Impurity 70 (CAS CATO-C4X-106870)
- Imatinib Impurity 65 (CAS CATO-C4X-106865)
- Imatinib Impurity 73 (CAS CATO-C4X-106873)
- Imatinib Impurity 87 (CAS 571187-02-5)
- Imatinib EP Impurity C (CAS 404844-02-6)
- Imatinib Impurity 2 (CAS 796738-74-4)
- Imatinib Impurity 24 (CAS 404844-11-7)
- Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8) (CAS 1185103-28-9)
Recommended Standards
- Ibrutinib Impurity 75 (CAS 2437254-47-0)
- Ademetionine Impurity 2 (CAS CATO-C4X-21522)
- Ibrutinib Impurity 72 (CAS CATO-C4X-106472)
- Adenosine Impurity 12 (CAS CATO-C4X-241912)
- Empagliflozin Impurity 135 (CAS 2760767-62-0)
- Cefoperazone EP Impurity B (CAS 711598-76-4)
- Docetaxel Impurity 55 (CAS 173101-59-2)
- N-(3-cyanophenyl)-2-methylpropanamide (CAS 900710-59-0)
- 4-(4-(3-(Pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)benzoic acid (CAS 1356614-53-3)
- 5-Chloro-3-hydroxybenzo[b]thiophene-2-carboxylic acid (CAS 1782408-48-3)
- 2-Amino-3,4,8-Trimethyl-3H-Imidazo[4,5-F]Quinoxaline (CAS 95896-78-9)
- 2-Chloro-6-vinylnaphthalene (CAS 96221-54-4)
- (5E)-5-[(6-Chloropyridin-3-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 866154-45-2)
- Des-Ile12-Aib13-Tirzepatide (CAS CATO-CPTD788960)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com