Topiroxostat Impurity 10 CAS 2044702-36-3
| CAS No. | 2044702-36-3 |
| Molecular Formula | C13H9N5O2 |
| Molecular Weight | 267.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Topiroxostat Impurity 10 (CAS 2044702-36-3) is a certified pharmaceutical impurity reference standard with the molecular formula C13H9N5O2 and a molecular weight of 267.24 g/mol.
Structurally, Topiroxostat Impurity 10 (C13H9N5O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 267.24 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H9N5O2 |
| Molecular Weight | 267.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 5 |
Related Topiroxostat Standards
- Topiroxostat Impurity 65 (CAS CATO-C4X-105565)
- Topiroxostat Impurity 11 (CAS CATO-C4X-105511)
- Topiroxostat Impurity 28 (CAS 1992028-94-0)
- Topiroxostat Impurity 38 (CAS 1841081-71-7)
- Topiroxostat Impurity 15 (CAS 577778-82-6)
- Topiroxostat Impurity 58 (CAS CATO-C4X-105558)
- Topiroxostat Impurity 18 (CAS CATO-C4X-105518)
- Topiroxostat Impurity 67 (CAS CATO-C4X-105567)
Recommended Standards
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- Custom peptides (CAS CATO-CPTD788509)
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