Fasudil Impurity 5 CAS 2044702-91-0
| CAS No. | 2044702-91-0 |
| Molecular Formula | C10H9NO3S |
| Molecular Weight | 223.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Fasudil Impurity 5 (C10H9NO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Fasudil Impurity 5 (CAS 2044702-91-0, C10H9NO3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Fasudil Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9NO3S |
| Molecular Weight | 223.25 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fasudil Standards
- Fasudil Impurity N1 (CAS 88551-85-3)
- Fasudil Impurity 31 (CAS CATO-C4X-136531)
- Fasudil Impurity 57 (CAS 146257-38-7)
- Fasudil Impurity 69 (CAS CATO-C4X-136569)
- Fasudil Impurity 23 (CAS 84468-15-5)
- Fasudil Impurity 12 (CAS 1211517-62-2)
- Fasudil Impurity 13 (CAS 748752-50-3)
- Fasudil Impurity 44 (CAS 84468-22-4)
Recommended Standards
- Posaconazole Impurity 153 (CAS 13578-51-3)
- Argatroban Impurity 30 (CAS 153886-69-2)
- Pioglitazone Impurity 8 (CAS 74772-78-4)
- Argatroban Impurity 2 (CAS CATO-C4X-10072)
- Resmetirom Impurity 98 (CAS 920509-68-8)
- Arotinolol Impurity 37 (CAS CATO-C4X-185437)
- Lasmiditan Impurity 56 (CAS CATO-C4X-247856)
- N-Nitroso Midazolam EP Impurity J (CAS CATO-C4X-150939)
- Ethyl 2-(2,5-difluorophenyl)-2-(methylamino)acetate (CAS 1218662-81-7)
- Benzo[d]thiazol-2-yl(1-oxa-4-thia-8-azaspiro[4.5]decan-8-yl)methanone (CAS 1351658-61-1)
- 3,3,3-trifluoro-1-(5-fluoro-1H-indol-3-yl)propan-1-one (CAS 1480459-88-8)
- Methyl 6-methoxy-4-oxo-3,4-dihydrophthalazine-1-carboxylate (CAS 53960-11-5)
- 3,3-Dimethyl-2,3-dihydro-1H-indole-6-sulfonic acid (CAS 1316066-02-0)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
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