Posaconazole Impurity 153 CAS 13578-51-3
| CAS No. | 13578-51-3 |
| Molecular Formula | C9H9N3O2S |
| Molecular Weight | 223.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Posaconazole Impurity 153 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Posaconazole Impurity 153 (CAS 13578-51-3) is a certified pharmaceutical impurity reference standard with the molecular formula C9H9N3O2S and a molecular weight of 223.25 g/mol.
The molecular framework of Posaconazole Impurity 153 (C9H9N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H9N3O2S |
| Molecular Weight | 223.25 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Posaconazole Standards
- Posaconazole Impurity 81 (CAS 165115-73-1)
- Posaconazole Impurity 265 (CAS CATO-C4X-1208265)
- Posaconazole Impurity 112 (CAS 110931-77-6)
- Posaconazole impurity 242 (CAS CATO-C4X-1208242)
- Posaconazole Impurity 84 (CAS 122151-32-0)
- Posaconazole Impurity 174 (CAS 2169241-14-7)
- Posaconazole Impurity 175 (CAS 169265-99-0)
- Posaconazole Impurity 33 (CAS 170985-85-0)
Recommended Standards
- Argatroban Impurity 30 (CAS 153886-69-2)
- Fasudil Impurity 31 (CAS CATO-C4X-136531)
- Argatroban Impurity 2 (CAS CATO-C4X-10072)
- Fasudil Impurity 5 (CAS 2044702-91-0)
- Dasatinib Impurity 22 (CAS CATO-C4X-160722)
- Mesilate Impurity 11 (CAS CATO-C4X-224711)
- Betahistine impurity 31 (CAS 91029-17-3)
- [Ser25] Protein Kinase C (19-31) (CAS 136795-05-6)
- 2-Bromo-4-fluoro-5-methoxyaniline (CAS 420786-92-1)
- 8-Chloroquinolin-5-amine hydrochloride (CAS 1156980-60-7)
- N-(Biotin-PEG4)-N-bis(PEG4-Boc) (CAS 2112730-79-5)
- 1H-Benzo[d][1,2,3]triazole-5-carbonitrile (CAS 24611-70-9)
- 5,7-Dimethyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one (CAS 698973-85-2)
- D-[His]1-Semaglutide (CAS CATO-C4X-222652)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com