Vortioxetine Impurity 119 CAS 204862-91-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.204862-91-9
Molecular FormulaC44H32OP2
Molecular Weight638.67 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Vortioxetine Impurity 119 CAS 204862-91-9 chemical structure

Description

As a process- or degradation-related impurity, Vortioxetine Impurity 119 (CAS 204862-91-9, C44H32OP2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Vortioxetine Impurity 119 (C44H32OP2) contains organophosphorus functionality, a hydroxyl group, an ether linkage, a polycyclic aromatic system. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC44H32OP2
Molecular Weight638.67 g/mol
Purity>95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)29.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2015

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