2-Chloro-3,5-difluorophenol CAS 206986-81-4

Purity 97%+In StockPharmaceutical Standards
CAS No.206986-81-4
Molecular FormulaC6H3ClF2O
Molecular Weight164.54 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-3,5-difluorophenol CAS 206986-81-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 164.54 g/mol gives 2-Chloro-3,5-difluorophenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-Chloro-3,5-difluorophenol (CAS 206986-81-4), a certified reference material (molecular formula C6H3ClF2O, MW 164.54 g/mol) for analytical method development and quality control.

The molecular framework of 2-Chloro-3,5-difluorophenol (C6H3ClF2O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Chloro-3,5-difluorophenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H3ClF2O
Molecular Weight164.54 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2016
Halogen ContentF/Cl-containing

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