Piroxicam Impurity 15 CAS 208051-67-6
| CAS No. | 208051-67-6 |
| Molecular Formula | C12H13NO5S |
| Molecular Weight | 283.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Piroxicam Impurity 15 (CAS 208051-67-6) is a certified pharmaceutical impurity reference standard with the molecular formula C12H13NO5S and a molecular weight of 283.30 g/mol.
Piroxicam Impurity 15 (C12H13NO5S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Piroxicam Impurity 15 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13NO5S |
| Molecular Weight | 283.30 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Piroxicam Standards
- Piroxicam EP Impurity K(Meloxicam EP Impurity A) (CAS 24683-26-9)
- Piroxicam EP Impurity F (CAS 76508-37-7)
- Piroxicam EP Impurity I (CAS 76508-35-5)
- Piroxicam Impurity 14 (CAS CATO-C4X-173314)
- Piroxicam EP Impurity L(Meloxicam EP Impurity F) (CAS 118854-48-1)
- Piroxicam Impurity 20 (CAS CATO-C4X-173320)
- Piroxicam EP Impurity J (CAS 35511-15-0)
- Piroxicam EP Impurity E (CAS 24683-20-3)
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