Piroxicam EP Impurity I CAS 76508-35-5
| CAS No. | 76508-35-5 |
| Molecular Formula | C12H13NO5S |
| Molecular Weight | 283.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Piroxicam EP Impurity I (CAS 76508-35-5, C12H13NO5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Piroxicam EP Impurity I (C12H13NO5S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Piroxicam EP Impurity I under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13NO5S |
| Molecular Weight | 283.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Piroxicam Standards
- Piroxicam EP Impurity K(Meloxicam EP Impurity A) (CAS 24683-26-9)
- Piroxicam Impurity 15 (CAS 208051-67-6)
- Piroxicam EP Impurity F (CAS 76508-37-7)
- Piroxicam Impurity 14 (CAS CATO-C4X-173314)
- Piroxicam EP Impurity L(Meloxicam EP Impurity F) (CAS 118854-48-1)
- Piroxicam Impurity 20 (CAS CATO-C4X-173320)
- Piroxicam EP Impurity J (CAS 35511-15-0)
- Piroxicam EP Impurity E (CAS 24683-20-3)
Recommended Standards
- 3-(((3,5-Dimethyl-4-nitro-1h-pyrazol-1-yl)methyl)thio)-5-methyl-4h-1,2,4-triazol-4-amine (CAS 1001519-09-0)
- Tert-butyl (R)-2-(2,5-difluorophenyl)pyrrolidine-1-carboxylate (CAS 1218935-58-0)
- 1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 1227269-45-5)
- Flurbiprofen Impurity 17 (CAS 78543-08-5)
- Gadoxetate Trisodium impurity 28 (CAS CATO-C4X-261828)
- Levofloxacin Impurity 22 (CAS 82419-46-3)
- Rufinamide Impurity 7 (CAS CATO-C4X-23397)
- 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 68373-65-9)
- PFTU (CAS 206190-14-9)
- (2,6-Dichloropyridin-4-yl)(morpholino)methanone (CAS 57803-44-8)
- N-Cbz-1-phenylcyclopropanamine (CAS 1324000-40-9)
- 2,5-Dioxaspiro[3.4]octan-8-one (CAS 2137714-50-0)
- 1-Cyclohexyl-3-(4-iodophenyl)urea (CAS 287185-29-9)
- Semaglutide impurity 32 (CAS CATO-C4X-222632)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com