Travoprost Impurity 15 CAS 208111-99-3
| CAS No. | 208111-99-3 |
| Molecular Formula | C25H23F3O6 |
| Molecular Weight | 476.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Travoprost Impurity 15 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Travoprost Impurity 15 (CAS 208111-99-3), a pharmacopoeial impurity reference standard (molecular formula C25H23F3O6, MW 476.45 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Travoprost Impurity 15 (C25H23F3O6) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C25H23F3O6 |
| Molecular Weight | 476.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Halogen Content | F-containing |
Related Travoprost Standards
- Travoprost Impurity 17 (CAS 208114-58-3)
- Travoprost Impurity 44 (CAS CATO-C4X-192544)
- Travoprost Impurity 45 (CAS CATO-C4X-192545)
- Travoprost Impurity 24（Fluprostenol Methyl Ester） (CAS 73275-76-0)
- Travoprost Impurity 20 (CAS 1642863-99-7)
- Travoprost Impurity 21 (CAS CATO-C4X-192521)
- Travoprost Acid-d4 (CAS 282550-19-0)
- Travoprost Impurity 43 (CAS CATO-C4X-192543)
Recommended Standards
- N-[(4-Fluorophenyl)methyl]-1-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321848-22-0)
- N-(9-Phenyl-9H-selenoxanthen-9-yl)benzenesulfonamide (CAS 82238-30-0)
- Relugolix Impurity 96 (CAS CATO-C4X-242996)
- Methyl 4-(3-(3-fluoro-4-methoxybenzoyl)-4-hydroxy-5-oxo-1-(pyridin-3-ylmethyl)-2,5-dihydro-1H-pyrrol-2-yl)benzoate (CAS 618074-85-4)
- Lamotrigine EP Impurity C (CAS 94213-23-7)
- Ceftriaxone Oxide Impurity (CAS 97466-28-9)
- Bupropion Impurity 53 HCl (CAS 1193779-34-8（free base）)
- 2-Chloro-N,N-diethyl-4-fluoro-3-methoxybenzamide (CAS 2586126-02-3)
- 2-(Benzenesulfinyl)ethan-1-amine hydrochloride (CAS 60523-52-6)
- [DAla2,DMet5] Enkephalin (CAS 100929-50-8)
- N-(2-(Furan-2-yl)-2-(indolin-1-yl)ethyl)cyclopropanecarboxamide (CAS 898458-10-1)
- 4-(7-Chloroquinolin-4-yl)morpholine hydrochloride (CAS 853344-40-8)
- 3-Cyclopropoxy-4-isopropyl-N,N-dimethylpyridin-2-amine (CAS 1243370-56-0)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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