Travoprost Impurity 20 CAS 1642863-99-7
| CAS No. | 1642863-99-7 |
| Molecular Formula | C24H33F3O5Si |
| Molecular Weight | 486.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Travoprost Impurity 20 (CAS 1642863-99-7) is a certified pharmaceutical impurity reference standard with the molecular formula C24H33F3O5Si and a molecular weight of 486.60 g/mol.
Based on its molecular formula C24H33F3O5Si, Travoprost Impurity 20 contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 486.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H33F3O5Si |
| Molecular Weight | 486.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Related Travoprost Standards
- Travoprost Impurity 21 (CAS CATO-C4X-192521)
- Travoprost Impurity 15 (CAS 208111-99-3)
- Travoprost Impurity 17 (CAS 208114-58-3)
- Travoprost 15-Keto Derivative (CAS 404830-45-1)
- Travoprost Impurity 44 (CAS CATO-C4X-192544)
- Travoprost Impurity 45 (CAS CATO-C4X-192545)
- Travoprost Enantiomer (CAS 340181-93-3)
- Travoprost (CAS 157283-68-6)
Recommended Standards
- Methylprednisolone Impurity 51 (CAS CATO-C4X-191951)
- Bazedoxifene N-Oxide (CAS 1174289-22-5)
- Prednisolone 21-Acetate 17-Valerate (CAS 72064-79-0)
- rac-Repaglinide USP Related Compound C (CAS 107362-12-9)
- Anagrelide Impurity 2 (CAS 1020243-02-0)
- Irinotecan Impurity 64 (CAS CATO-C4X-166764)
- Amiodarone EP Impurity G (CAS 1087223-70-8)
- 4-(Piperazin-1-ylmethyl)benzene-1,2,3-triol (CAS 78800-37-0)
- 3-(Diethylamino)benzoic acid (CAS 25642-60-8)
- 4-[(2-methoxyethyl)amino]benzoic acid (CAS 855199-07-4)
- 2-(Butylthio)-6-(phenylthio)pyrimidin-4-amine (CAS 284681-95-4)
- 1,2,3,4-Tetrahydronaphthalene-2,3-diol (CAS 6970-78-1)
- 2-Chloro-4-nitro-1-(trichloromethoxy)benzene (CAS 1417567-12-4)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
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