Prostaglandin Impurity 16 CAS 20836-85-5
| CAS No. | 20836-85-5 |
| Molecular Formula | C7H7ClO |
| Molecular Weight | 142.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Prostaglandin Impurity 16 (CAS 20836-85-5), a pharmacopoeial impurity reference standard (molecular formula C7H7ClO, MW 142.58 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Prostaglandin Impurity 16 (C7H7ClO) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7ClO |
| Molecular Weight | 142.58 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
Related Prostaglandin Standards
- Prostaglandin Impurity 15 (CAS 5307-99-3)
- Prostaglandin Impurity 17 (CAS 63319-59-5)
- Prostaglandin E1 sodium (CAS 27930-45-6)
- Prostaglandin I3 (sodium) (CAS 68324-96-9)
- Prostaglandin Impurity 1 (CAS 240405-20-3)
- Δ-12 Prostaglandin J2 (CAS 87893-54-7)
- Prostaglandin Impurity 27 (CAS 60203-57-8)
- 15-epi Prostaglandin A1 (CAS 20897-92-1)
Recommended Standards
- p-Chloro-m-cresol (CAS 35421-08-0)
- 2-Chloro-6-Methylphenol (CAS 87-64-9)
- 2-Chlorobenzyl alcohol (CAS 17849-38-6)
- 4-Chloro-3-Methylphenol (CAS 59-50-7)
- Sacubitril impurity 15 (CAS CATO-C4X-280915)
- Edoxaban Impurity 122 (CAS CATO-C4X-1063122)
- Roxadustat Impurity 133 (CAS 2776-60-5)
- Dasatinib Impurity 2 (CAS 910297-52-8)
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- tert-Butyl N-[trans-4-(trifluoromethyl)pyrrolidin-3-yl]carbamate (CAS 168544-95-4)
- N-(3-Chloro-4-cyano-2-methylphenyl)acetamide (CAS 627531-48-0)
- 3-(2,6-Dimethylphenyl)-3-trifluoromethyl-propiophenone (CAS 898755-06-1)
- 1-(Benzo[d][1,3]dioxol-5-ylmethyl)-N-methylpiperidin-4-amine hydrochloride (CAS 1417793-64-6)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com