Prostaglandin Impurity 15 CAS 5307-99-3
| CAS No. | 5307-99-3 |
| Molecular Formula | C7H6Cl2O |
| Molecular Weight | 177.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Prostaglandin Impurity 15 (C7H6Cl2O) contains a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 177.03 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Prostaglandin Impurity 15 (CAS 5307-99-3), a pharmacopoeial impurity reference standard (molecular formula C7H6Cl2O, MW 177.03 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6Cl2O |
| Molecular Weight | 177.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Prostaglandin Standards
- Prostaglandin Impurity 17 (CAS 63319-59-5)
- Prostaglandin Impurity 16 (CAS 20836-85-5)
- Prostaglandin Impurity 1 (CAS 240405-20-3)
- Δ-12 Prostaglandin J2 (CAS 87893-54-7)
- Prostaglandin Impurity 27 (CAS 60203-57-8)
- 15-epi Prostaglandin A1 (CAS 20897-92-1)
- Prostaglandin F2α 1,15-lactone (CAS 55314-49-3)
- Prostaglandin F2α; 1,11-lactone (CAS 62410-84-8)
Recommended Standards
- 2,4-Dichlorobenzyl Alcohol EP Impurity C (CAS 1805-32-9)
- 2,4-Dichlorobenzyl Alcohol EP Impurity A (CAS 34145-05-6)
- Abemaciclib impurity 116 (CAS CATO-C4X-2937116)
- Voriconazole Impurity 70 (CAS 115617-41-9)
- Coclaurine Impurity 16 (CAS CATO-C4X-27516)
- Ibrutinib Impurity 114 (CAS CATO-C4X-1064114)
- Desmethyl Fluorometholone (CAS 426-20-0)
- 4-Cyclopropylmethoxy-2-fluorobenzaldehyde (CAS 883525-65-3)
- (2,2,2-Trichloroacetyl)glycine (CAS 15166-50-4)
- 3-Cyano-2-phenylacetophenone (CAS 758710-68-8)
- (R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(2-bromophenyl)butanoic acid (CAS 788149-96-2)
- 4-(4-Bromo-3,5-dimethylphenyl)-2-methylbutane-1,2-diol (CAS 1699742-51-2)
- Tenofovir alafenamide Impurity 42 (CAS 2053424-82-9)
- Glucagon (1-29) (CAS 16941-32-5)
Why CATO?
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