Vonoprazan Impurity 140 CAS 208984-17-2
| CAS No. | 208984-17-2 |
| Molecular Formula | C5H4N2O2 |
| Molecular Weight | 124.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Vonoprazan Impurity 140 is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 124.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Vonoprazan Impurity 140 (CAS 208984-17-2, C5H4N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Vonoprazan Impurity 140 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4N2O2 |
| Molecular Weight | 124.10 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2016 |
| Nitrogen Atoms | 2 |
Related Vonoprazan Standards
- Vonoprazan Impurity 139 (CAS CATO-C4X-1020139)
- Vonoprazan Impurity 134 (CAS 52334-53-9)
- Vonoprazan Impurity 135 (CAS 55717-46-9)
- Vonoprazan Fumarate Impurity 56 (CAS 445-27-2)
- Vonoprazan Impurity 215 (CAS 1993-03-9)
- Vonoprazan Impurity 133 (CAS 15128-82-2)
- Vonoprazan Impurity 129 (CAS 109-00-2)
- Vonoprazan Fumarate Impurity 15 (CAS 636-73-7)
Recommended Standards
- Pyrimidine-5-carboxylic Acid (CAS 4595-61-3)
- Nicotinic Acid EP Impurity H (CAS 2530-26-9)
- Nicotinic Acid- (CAS 57987-14-1)
- Pyrazinamide EP Impurity A (CAS 98-97-5)
- Budesonide impurity 46 (CAS 1831164-04-5)
- Minoxidil Impurity 10 (CAS 79459-04-4)
- Tunodafil Impurity 2 (CAS CATO-C4X-31102)
- (5-Chloro-2-methanesulfonylphenyl)boronic acid (CAS 1313617-73-0)
- 1-benzyl-6-chloro-1H-1,3-benzodiazol-2-amine (CAS 1545791-31-8)
- N-(2,5-dichlorophenyl)-3-oxobutanamide (CAS 2044-72-6)
- 4-(4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl)morpholine (CAS 1263216-16-5)
- 3-Bromo-5-hydroxy-4-methylbenzoic acid (CAS 1781975-10-7)
- 4-((2-Methylpentan-3-yl)amino)butan-2-ol (CAS 1343904-30-2)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
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