Vonoprazan Fumarate Impurity 56 CAS 445-27-2
| CAS No. | 445-27-2 |
| Molecular Formula | C8H7FO |
| Molecular Weight | 138.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Vonoprazan Fumarate Impurity 56 (CAS 445-27-2, C8H7FO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Vonoprazan Fumarate Impurity 56 (C8H7FO) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Vonoprazan Fumarate Impurity 56 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7FO |
| Molecular Weight | 138.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Vonoprazan Standards
- Vonoprazan Impurity 215 (CAS 1993-03-9)
- Vonoprazan Impurity 133 (CAS 15128-82-2)
- Vonoprazan Impurity 139 (CAS CATO-C4X-1020139)
- Vonoprazan Impurity 140 (CAS 208984-17-2)
- Vonoprazan Fumarate Impurity 15 (CAS 636-73-7)
- Vonoprazan Impurity 153 (CAS 15103-48-7)
- Vonoprazan Impurity 154 (CAS 5402-20-0)
- Vonoprazan Impurity N3 (CAS 15177-57-8)
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- Boc-Cholecystokinin Octapeptide (desulfated) (A-1295.0001) (CAS 25687-34-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com