Penicillamine EP Impurity A CAS 20902-45-8
| CAS No. | 20902-45-8 |
| Molecular Formula | C10H20N2O4S2 |
| Molecular Weight | 296.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Penicillamine EP Impurity A (CAS 20902-45-8, C10H20N2O4S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H20N2O4S2, Penicillamine EP Impurity A contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 296.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H20N2O4S2 |
| Molecular Weight | 296.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Penicillamine Standards
- DL-Penicillamine disulfide (CAS 312-10-7)
- Penicillamine Impurity 2 (CAS CATO-CP155169)
- Penicillamine Impurity 1 (CAS 856846-79-2)
- Penicillamine impurity 3 (CAS CATO-C4X-29233)
- L-Penicillamine-d6 (CAS 1795786-79-6)
- D-Penicillamine-d3 (CAS CATO-C4X-29234)
- L-Penicillamine (CAS 1113-41-3)
- D-Penicillamine (CAS 52-67-5)
Recommended Standards
- Noribogaine (CAS 481-88-9)
- S,s-butanediyldi-l-cysteine (CAS 50727-80-5)
- N-methyl-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine (CAS 290297-25-5)
- Tert-butyl 3-((cyclopropylamino)methyl)-3-hydroxy-8-azabicyclo[3.2.1]Octane-8-carboxylate (CAS 2097943-91-2)
- Nitrendipine Impurity 4 (CAS CATO-C4X-18344)
- Exemestane Impurity 36 (CAS CATO-C4X-164136)
- Atrasentan Impurity 199 (CAS CATO-C4X-3347199)
- 2-Amino-3-(3,4-dimethoxyphenyl)pyridine (CAS 663918-32-9)
- 1-Amino-7-bromo-2,3-dihydro-1H-indene (CAS 1071449-08-5)
- 17:0-14:1 PS (CAS 1036814-91-1)
- Ethyl 4-ethoxybenzoylformate (4-ethoxyphenyl)oxoacetic acid ethyl ester 70080-61-4 (CAS 70080-61-4)
- N-Trityl Candesartan Methoxy Analogue (CAS 1246820-94-9)
- 2626-52-0 3-(Diethylamino)propyl isothiocyanate diethyl(3-isothiocyanatopropyl)amine diethyl-(3-isothiocyanato-propyl)-amine (CAS 2626-52-0)
- Semaglutide impurity 92 (CAS CATO-C4X-222692)
Why CATO?
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