(2-chloro-4-phenoxyphenyl)-(4-(((3R,6S)-6-(hydroxymethyl)oxan-3-yl)amino)-7H-pyrrolo(2,3-d)pyrimidin-5-yl)methanone CAS 2095393-15-8
| CAS No. | 2095393-15-8 |
| Molecular Formula | C25H43ClN4O4 |
| Molecular Weight | 499.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2-chloro-4-phenoxyphenyl)-(4-(((3R,6S)-6-(hydroxymethyl)oxan-3-yl)amino)-7H-pyrrolo(2,3-d)pyrimidin-5-yl)methanone.
(2-chloro-4-phenoxyphenyl)-(4-(((3R,6S)-6-(hydroxymethyl)oxan-3-yl)amino)-7H-pyrrolo(2,3-d)pyrimidin-5-yl)methanone (CAS 2095393-15-8), molecular formula C25H43ClN4O4 and molecular weight 499.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2-chloro-4-phenoxyphenyl)-(4-(((3R,6S)-6-(hydroxymethyl)oxan-3-yl)amino)-7H-pyrrolo(2,3-d)pyrimidin-5-yl)methanone (C25H43ClN4O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2-chloro-4-phenoxyphenyl)-(4-(((3R,6S)-6-(hydroxymethyl)oxan-3-yl)amino)-7H-pyrrolo(2,3-d)pyrimidin-5-yl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H43ClN4O4 |
| Molecular Weight | 499.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrol-2-yl)hydrazine-1-carboxamide (CAS 338407-23-1)
- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1,4-diazepan-1-yl)(3-(2-chlorophenyl)-5-methylisoxazol-4-yl)methanone (CAS 1022094-73-0)
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- 2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)-N-(2,4-dichlorophenyl)acetamide (CAS 477845-11-7)
- 578743-87-0 AS1021 Chloro[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper(I) Copper, [1,3-bis[2,6-bis(1-methylethyl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene]chloro- Cu(IPr)Cl [(iPr)CuCl] [1,3-Bis(2,6-diisopropylphenyl)-1,3-dihydro-2H-imidazol-2-ylidene](chloro)copper [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper(I) chloride (CAS 578743-87-0)
- 3-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(2-(2,4-dichlorophenoxy)ethyl)-2-methyl-1H-indole (CAS 400074-07-9)
Recommended Standards
- Loratadine Impurity 51 (CAS CATO-C4X-142651)
- Ixazomib Impurity 72 (CAS CATO-C4X-126772)
- (S)-gne-140 (CAS 2003234-64-6)
- Tafamidis Impurity 2 (CAS CATO-C4X-28772)
- 3-Hydroxy-2,7-naphthalenedisulfonic Acid Sodium Salt > 90% (CAS 15883-57-5)
- 3-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1779124-56-9)
- 4-(azidomethyl)-3-fluorobenzonitrile (CAS 368426-24-8)
- N-[(E)-(3-Bromo-2-hydroxy-5-methoxyphenyl)methylidene]-2-furohydrazide (CAS 477848-04-7)
- 2-(1-Ethyl-2-methyl-1H-benzo[d]imidazol-5-yl)acetic acid (CAS 1119450-14-4)
- 2-[2-(cyanomethyl)phenyl]acetic acid (CAS 56066-94-5)
- 5-(Trifluoromethyl)quinazoline-2,4-diamine (CAS 133116-84-4)
- Ethyl 5-iodothiophene-3-carboxylate (CAS 1496383-74-4)
- 6-Chloro-2-(difluoromethyl)-5-methylpyridine-3-sulfonamide (CAS 1806870-57-4)
- Liraglutide Impurity 17 TFA Salt (CAS CATO-C4X-199217)
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