Menaquinone Impurity 48 CAS 20962-84-9
| CAS No. | 20962-84-9 |
| Molecular Formula | C11H6O4 |
| Molecular Weight | 202.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Menaquinone Impurity 48 (CAS 20962-84-9), a pharmacopoeial impurity reference standard (molecular formula C11H6O4, MW 202.16 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Menaquinone Impurity 48 (C11H6O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H6O4 |
| Molecular Weight | 202.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
Related Menaquinone Standards
- Menaquinone Impurity 3 (CAS 110327-29-2)
- Menaquinone impurity 16 (CAS 125411-11-2)
- Menaquinone impurity 14 (CAS 69729-17-5)
- Menaquinone Impurity 51 (CAS 77898-97-6)
- Menaquinone Impurity 46 (CAS 57766-68-4)
- Menaquinone impurity 23 (CAS 2387-69-1)
- Menaquinone Impurity 12 (CAS 3790-76-9)
- Menaquinone impurity 40 (CAS 3879-62-7)
Recommended Standards
- 2,2-Difluoro-3-hydroxy-(3-pyridyl)propionyl Amide 887354-60-1 |A,|A-Difluoro-|A-hydroxy-3-pyridinepropanamide (CAS 887354-60-1)
- Xanthotoxol (CAS 2009-24-7)
- Trimethyl ethene-1,1,2-tricarboxylate (CAS 51175-48-5)
- Bergaptol (CAS 486-60-2)
- Lasmiditan Impurity 52 (CAS CATO-C4X-247852)
- Cyanocobalamin EP Impurity A (CAS 23208-66-4)
- Anagrelide Impurity 11 (CAS 70380-50-6)
- 5-chloro-1,3,4-thiadiazole-2-carboxylic acid (CAS 1554480-49-7)
- 6-Bromo-1-methyl-1H-indazole-4-carbonitrile (CAS 1245465-10-4)
- (4,6-Dimethylpyrimidin-2-yl)proline (CAS 956614-59-8)
- N-Hexyl-N-(3-methyl-1,2,4-oxadiazol-5-yl)acetamide (CAS 62347-44-8)
- 6-Oxo-6-(2-(trifluoromethyl)phenyl)hexanoic acid (CAS 951888-87-2)
- 4-Methyl-N-(3-methylbenzyl)benzamide (CAS 710318-34-6)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com