Anagrelide Impurity 11 CAS 70380-50-6
| CAS No. | 70380-50-6 |
| Molecular Formula | C11H12Cl2N2O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Anagrelide Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Anagrelide Impurity 11 (CAS 70380-50-6), a pharmacopoeial impurity reference standard (molecular formula C11H12Cl2N2O4HCl, MW 343.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Anagrelide Impurity 11 (C11H12Cl2N2O4HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C11H12Cl2N2O4 HCl |
| Molecular Weight | 343.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Anagrelide Standards
- Anagrelide Impurity 39 (CAS 1003-56-1)
- Anagrelide Impurity 2 (CAS 1020243-02-0)
- Anagrelide 5-Acetoxy Impurity (CAS 1076198-71-4)
- Anagrelide impurity 25 (CAS 1092352-99-2)
- Anagrelide Impurity 12 (CAS 1159977-03-3)
- Anagrelide-13C3 (CAS 1219531-58-4)
- Anagrelide Impurity 24 (CAS 147249-41-0)
- Anagrelide Impurity 10 (CAS 147249-42-1)
Recommended Standards
- Sitagliptin Impurity 60 (CAS CATO-C4X-114460)
- Carbasalate EP Impurity D (CAS 552-94-3)
- Buspirone impurity 01 (CAS 105496-33-1)
- 2-Chloro-4-iodo-5-methyl-3-(trimethylsilyl)pyridine (CAS 1203499-34-6)
- Ethyl 2-Methyloxazole-4-carboxylate (CAS 10200-43-8)
- (E)-2-Cyano-N-(2,5-dichlorophenyl)-3-(5-(2-methylcyclopropyl)furan-2-yl)acrylamide (CAS 1164490-92-9)
- 2-Fluoro-6-methoxy-3-methylbenzaldehyde (CAS 1056214-68-6)
- Tetrahydro-11-deoxy Cortisol 3-O-beta-D-Glucuronide (CAS 56162-40-4)
- 4-ethyl-1,3,5-triazin-2-amine (CAS 30360-34-0)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
Why CATO?
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