Selitrectinib(LOXO-195) CAS 2097002-61-2
| CAS No. | 2097002-61-2 |
| Molecular Formula | C20H21FN6O |
| Molecular Weight | 380.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Selitrectinib(LOXO-195).
Selitrectinib(LOXO-195) (CAS 2097002-61-2), molecular formula C20H21FN6O and molecular weight 380.42 g/mol, is a CATO reference standard with documented purity and traceability.
Selitrectinib(LOXO-195) (C20H21FN6O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Selitrectinib(LOXO-195) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21FN6O |
| Molecular Weight | 380.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Recommended Standards
- Cenobamate Impurity 50 (CAS CATO-C4X-241650)
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- Cenobamate Impurity 49 (CAS CATO-C4X-241649)
- Benzyl (2R)-3-N,N-Dibenzylamino-2-fluoropropanoate-13C3 (CAS 1217853-98-9)
- Ethyl 2-(2-fluorophenyl)-7-oxo-7h-[1,2,4]triazolo[5,1-b][1,3]thiazine-5-carboxylate (CAS 747411-46-7)
- (3R,4S)-1-Cbz-4-methylpyrrolidine-3-carboxylic Acid (CAS 1428243-36-0)
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- 4-Fluoro-2-((hexyloxy)methyl)benzenethiol (CAS 1443345-86-5)
- (Propan-2-yl)[(2,4,5-trimethoxyphenyl)methyl]amine hydrochloride (CAS 1158632-50-8)
- 1-Chloro-2-(ethylsulfonyl)benzene (CAS 57321-29-6)
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- BOc-l-leucine-o cesium salt (CAS 42538-67-0)
- 1-(1H-imidazol-1-yl)propan-2-amine (CAS 924714-15-8)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
Why CATO?
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