1-Chloro-2-(ethylsulfonyl)benzene CAS 57321-29-6
| CAS No. | 57321-29-6 |
| Molecular Formula | C8H9ClO2S |
| Molecular Weight | 204.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 204.67 g/mol gives 1-Chloro-2-(ethylsulfonyl)benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-Chloro-2-(ethylsulfonyl)benzene (CAS 57321-29-6), a certified reference material (molecular formula C8H9ClO2S, MW 204.67 g/mol) for analytical method development and quality control.
Structurally, 1-Chloro-2-(ethylsulfonyl)benzene (C8H9ClO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 204.67 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9ClO2S |
| Molecular Weight | 204.67 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-methyl-1-(methylsulfonyl)benzene (CAS 10200-36-9)
- 2-chloro-4,5-dimethoxybenzene-1-thiol (CAS 1094359-76-8)
- Methyl 4-chloro-5-ethylthiophene-2-carboxylate (CAS 1399655-29-8)
- 4-Chloro-5-propylthiophene-2-carboxylic acid (CAS 1399660-65-1)
- 2-Chloro-1-methyl-4-(methylsulfonyl)benzene (CAS 1671-18-7)
- 1-Chloro-3-ethanesulfonylbenzene (CAS 494870-50-7)
- 1-Chloro-4-(ethylsulfonyl)benzene (CAS 7205-80-3)
- Ethyl 5-chloro-4-methylthiophene-2-carboxylate (CAS 74598-04-2)
Recommended Standards
- 1-((Chloromethyl)sulfonyl)-4-methylbenzene (CAS 7569-26-8)
- (2-Chloroethylsulfonyl)benzene (CAS 938-09-0)
- 2,5-Dimethylbenzene-1-sulfonyl chloride (CAS 19040-62-1)
- 1-Chloromethyl-3-methanesulfonylbenzene (CAS 586373-70-8)
- 2-Phenyl-2-(piperidin-4-yl)acetonitrile hydrochloride (CAS 83898-13-9)
- 7-[2-Hydroxy(propyl-d6)]guanine (CAS 1346599-30-1)
- 2-(Cyclopentylamino)ethan-1-ol hydrochloride (CAS 1193389-76-2)
- Atropine Impurity 34 (CAS 101723-82-4)
- 3-(4-Hydroxypiperidin-1-yl)-3-oxopropanenitrile (CAS 129999-83-3)
- N-((1R,2R)-2-amino-1,2-diphenylethyl)-2,3,4,5,6-pentafluorobenzenesulfonamide (CAS 1026785-12-5)
- N-Desinethyldoxepin–d3 HCl (CAS 1331665-54-3)
- Thieno[3,2-b]pyridine-3-carbaldehyde (CAS 1369237-95-5)
- 2-Cyclohexyl-1-(oxazol-2-yl)ethan-1-one (CAS 898759-04-1)
- D-Phe22-Tirzepatide (CAS CATO-CPTD788912)
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