Carbidopa Impurity 35 CAS 2104012-68-0
| CAS No. | 2104012-68-0 |
| Molecular Formula | C11H14O4 |
| Molecular Weight | 210.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Carbidopa Impurity 35.
Carbidopa Impurity 35 (CAS 2104012-68-0) is a certified pharmaceutical impurity reference standard with the molecular formula C11H14O4 and a molecular weight of 210.23 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Carbidopa Impurity 35 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 210.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14O4 |
| Molecular Weight | 210.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
Related Carbidopa Standards
- Carbidopa EP Impurity A (CAS 555-30-6)
- Carbidopa Impurity 6 (CAS 210576-58-2)
- Carbidopa Impurity 33 (CAS CATO-C4X-231033)
- Carbidopa Impurity 15 (CAS 579-27-1)
- Carbidopa Impurity 4 (CAS 306748-61-8)
- Carbidopa Impurity 12 (CAS 53832-94-3)
- Carbidopa EP Impurity B (CAS 18181-08-3)
- Carbidopa Impurity 5 (CAS 54737-52-9)
Recommended Standards
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