Orforglipron Impurity 54 CAS 210536-89-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.210536-89-3
Molecular FormulaC21H20N2
Molecular Weight300.40 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Orforglipron Impurity 54 CAS 210536-89-3 chemical structure

Description

Orforglipron Impurity 54 (CAS 210536-89-3) is a certified pharmaceutical impurity reference standard with the molecular formula C21H20N2 and a molecular weight of 300.40 g/mol.

The molecular framework of Orforglipron Impurity 54 (C21H20N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Orforglipron Impurity 54 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC21H20N2
Molecular Weight300.40 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2017
Nitrogen Atoms2

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