Orforglipron impurity 134 CAS CATO-C4X-3234134
| CAS No. | CATO-C4X-3234134 |
| Molecular Formula | C8H9Br2FN2 |
| Molecular Weight | 311.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Orforglipron impurity 134 (C8H9Br2FN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 311.98 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Orforglipron impurity 134 (CAS CATO-C4X-3234134), a pharmacopoeial impurity reference standard (molecular formula C8H9Br2FN2, MW 311.98 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9Br2FN2 |
| Molecular Weight | 311.98 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Orforglipron Standards
- Orforglipron impurity 29 (CAS CATO-C4X-323429)
- Orforglipron Impurity 54 (CAS 210536-89-3)
- Orforglipron impurity 133 (CAS CATO-C4X-3234133)
- Orforglipron impurity 26 (CAS 2860499-50-7)
- Orforglipron impurity 100 (CAS CATO-C4X-3234100)
- Orforglipron impurity 135 (CAS 2384281-38-1)
- Orforglipron Impurity 57 (CAS CATO-C4X-323457)
- Orforglipron Impurity 58 (CAS 2212021-58-2)
Recommended Standards
- 3,4-Dichloro-5-(2,4-dichlorophenoxy)-1-methyl-1H-pyrazole (CAS 400081-47-2)
- 2-(4-Bromo-2-chlorophenoxy)butanoyl chloride (CAS 1160257-42-0)
- 5-Bromo-3-(piperidine-1-carbonyl)phenylboronic acid (CAS 2121514-06-3)
- 2-(4-Bromo-2-chlorophenoxy)-2-methylpropanoyl chloride (CAS 1160257-74-8)
- Lenalidomide Impurity 34 (CAS CATO-C4X-190334)
- Aripiprazole Impurity 89 (CAS CATO-C4X-100889)
- Pretomanid Impurity 24 (CAS CATO-C4X-260624)
- 4-(4-Bromophenyl)-2-(4-chlorophenyl)-4-oxobutanenitrile (CAS 344281-57-8)
- N2,N2-dimethyl-3-(trifluoromethyl)pyridine-2,5-diamine (CAS 288247-16-5)
- 1-(4-Methoxybenzyl)thiourea (CAS 37412-64-9)
- Ramoplanin (CAS 76168-82-6)
- 4,4-Difluoro-1,4'-bipiperidine (CAS 686298-08-8)
- 1-(tert-Butoxycarbonyl)-1H-indole-6-carboxylic acid (CAS 208772-42-3)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com