Orforglipron impurity 125 CAS 3103103-07-4
| CAS No. | 3103103-07-4 |
| Molecular Formula | C15H19FN4 |
| Molecular Weight | 274.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 274.34 g/mol gives Orforglipron impurity 125 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Orforglipron impurity 125 (CAS 3103103-07-4, C15H19FN4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Orforglipron impurity 125 (C15H19FN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 274.34 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Orforglipron impurity 125 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H19FN4 |
| Molecular Weight | 274.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Orforglipron Standards
- Orforglipron Impurity 58 (CAS 2212021-58-2)
- Orforglipron impurity 135 (CAS 2384281-38-1)
- Orforglipron Impurity 54 (CAS 210536-89-3)
- Orforglipron impurity 136 (CAS 2274775-42-5)
- Orforglipron impurity 140 (CAS 757247-91-9)
- Orforglipron impurity 35 (CAS 7254-19-5)
- Orforglipron impurity 22 (CAS 3047293-07-9)
- Orforglipron Impurity 40 (CAS CATO-C4X-323440)
Recommended Standards
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- Alogliptin impurity 77 HCl (CAS 1108732-05-3（free base）)
- Vonoprazan Impurity 169 (CAS CATO-C4X-1020169)
- Bexagliflozin Impurity 12 (CAS CATO-C4X-332212)
- Ethyl 2-[(3-benzamido-1H-1,2,4-triazol-5-yl)sulfanyl]acetate (CAS 866010-95-9)
- (2-(3-Methylpiperidin-1-yl)pyridin-4-yl)boronic acid (CAS 2225152-63-4)
- Methanone, (4-bromophenyl)(2,3-dihydro-1,4-benzodioxin-6-yl)- (CAS 101018-99-9)
- Heptane-3-sulfonamide (CAS 1340378-68-8)
- Ampicillin Impurity 50 (CAS CATO-C4X-144350)
- 2-Bromo-4-ethylbenzaldehyde (CAS 1289148-61-3)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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