Tofacitinib Impurity 166 DiHCl CAS 2106832-55-5

Description

Compared with other compounds in its class, the molecular weight of 254.80 g/mol gives Tofacitinib Impurity 166 DiHCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Tofacitinib Impurity 166 DiHCl (CAS 2106832-55-5) is a certified pharmaceutical impurity reference standard with the molecular formula C14H22N2HCl and a molecular weight of 254.80 g/mol.

Structurally, Tofacitinib Impurity 166 DiHCl (C14H22N2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 254.80 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Tofacitinib Impurity 166 DiHCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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