Tofacitinib Impurity 38 CAS 1092578-45-4
| CAS No. | 1092578-45-4 |
| Molecular Formula | C20H25N5 |
| Molecular Weight | 335.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tofacitinib Impurity 38.
CATO supplies Tofacitinib Impurity 38 (CAS 1092578-45-4), a pharmacopoeial impurity reference standard (molecular formula C20H25N5, MW 335.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tofacitinib Impurity 38 (C20H25N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 335.45 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tofacitinib Impurity 38 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H25N5 |
| Molecular Weight | 335.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 5 |
Related Tofacitinib Standards
- Tofacitinib Impurity 228 (CAS CATO-C4X-1079228)
- Tofacitinib Impurity 37 (CAS 1252883-90-1)
- Tofacitinib Impurity 39 (CAS 2459302-80-6)
- Tofacitinib Impurity 4 (CAS 477600-73-0)
- Tofacitinib Impurity 162 (CAS CATO-C4X-1079162)
- Tofacitinib Impurity 65 (CAS CATO-C4X-107965)
- Tofacitinib Impurity 32 (CAS CATO-C4X-107932)
- Tofacitinib Impurity 238 (CAS CATO-C4X-1079238)
Recommended Standards
- N-(1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 384337-90-0)
- 4-Butoxy-N-(sec-butyl)naphthalene-1-sulfonamide (CAS 1007688-35-8)
- 2-Amino-6-(naphthalen-2-ylthio)quinazoline-4(1H)-thione (CAS 52978-99-1)
- N-(2-(Dimethylamino)-2-(1-methyl-1H-pyrrol-2-yl)ethyl)-1-(m-tolyl)methanesulfonamide (CAS 1049419-28-4)
- Mirogabalin Impurity 46 Formate Salt (CAS 2165847-73-2 (free base))
- Ampicillin Impurity 73 (CAS CATO-C4X-144373)
- Fenoterol EP Impurity B (Enantiomer Mixture)HCl (CAS 1944-11-2)
- Eudesmin (CAS 526-06-7)
- 5-Bromo-6-cyclopropylpyrimidin-4-ol (CAS 27192-20-7)
- 4-Bromo-3-(trifluoromethoxy)-2-(trifluoromethyl)aniline (CAS 1804873-78-6)
- 5-(2-Chlorobenzyl)-N-methyl-1,3,4-thiadiazol-2-amine (CAS 87410-84-2)
- 1-(propan-2-yl)-1H-1,2,4-triazole-5-carboxylic acid (CAS 1198436-87-1)
- 6-Bromo-2-chloro-1,7-naphthyridine (CAS 1246554-46-0)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com