Dabigatran Impurity 6 CAS 211915-00-3
| CAS No. | 211915-00-3 |
| Molecular Formula | C33H39N7O5 |
| Molecular Weight | 613.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Dabigatran Impurity 6 (CAS 211915-00-3, C33H39N7O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Dabigatran Impurity 6 (C33H39N7O5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C33H39N7O5 |
| Molecular Weight | 613.71 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2017 |
| Nitrogen Atoms | 7 |
Related Dabigatran Standards
- Dabigatran Impurity N1 (CAS 1416446-45-1)
- Dabigatran Impurity 49 (CAS CATO-C4X-108949)
- Dabigatran Impurity 73 (CAS CATO-C4X-108973)
- Dabigatran Impurity 20 (CAS 1408238-37-8)
- DABIGATRAN ETEXILATE (CAS 1610666-09-5)
- Dabigatran Impurity 11 (CAS 1610758-20-7)
- Dabigatran Impurity 125 (CAS 2225986-94-5)
- Dabigatran impurity 140 (CAS 1873316-01-8)
Recommended Standards
- (S)-(2-((Bis(3,5-dimethylphenyl)phosphanyl)methyl)pyrrolidin-1-yl)(2-(diphenylphosphanyl)phenyl)methanone (CAS 2755107-32-3)
- N-[(8α,9S)-10,11-Dihydro-6'-methoxycinchonan-9-yl]-2-(diphenylphosphino)benzamide (CAS 1630973-06-6)
- N-[(9R)-10,11-Dihydro-6'-methoxycinchonan-9-yl]-2-(diphenylphosphino)benzamide (CAS 1808117-30-7)
- Acetyl Tetrapeptide- 15 (CAS 928007-64-1)
- Methylene blue Impurity 8 (CAS 2204245-78-1)
- Clemastine Impurity 17 (CAS CATO-C4X-183717)
- Labetalol EP Impurity D (CAS CATO-C1829030)
- Ethyl 5,8-Dihydroxyimidazo[1,5-a]pyrazine-1-carboxylate (CAS 1256633-37-0)
- 4-((3-Chloro-4-fluorobenzyl)oxy)benzaldehyde (CAS 1443345-69-4)
- 2-Amino-4-(aminomethyl)-6-(difluoromethyl)nicotinonitrile (CAS 1805210-08-5)
- 5-Hydroxy-6,7-dimethoxy-2-phenyl-4H-chromen-4-one (CAS 740-33-0)
- 2,6-Dichloro-3-fluorobenzotrifluoride (CAS 1804514-55-3)
- 2,4-Dichloro-5-methylphenacyl bromide (CAS 1806347-72-7)
- Semaglutide impurity 100 (CAS CATO-C4X-2226100)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com