5-Chloro-4-hydroxy-3-(trifluoromethyl)phenylboronic acid CAS 2121511-51-9

Purity 97%+In StockPharmaceutical Standards
CAS No.2121511-51-9
Molecular FormulaC7H5BClF3O3
Molecular Weight240.37 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Chloro-4-hydroxy-3-(trifluoromethyl)phenylboronic acid CAS 2121511-51-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-4-hydroxy-3-(trifluoromethyl)phenylboronic acid.

CATO supplies 5-Chloro-4-hydroxy-3-(trifluoromethyl)phenylboronic acid (CAS 2121511-51-9), a certified reference material (molecular formula C7H5BClF3O3, MW 240.37 g/mol) for analytical method development and quality control.

Structurally, 5-Chloro-4-hydroxy-3-(trifluoromethyl)phenylboronic acid (C7H5BClF3O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 240.37 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H5BClF3O3
Molecular Weight240.37 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1997
Halogen ContentF/Cl-containing

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