(2-Chloro-4-trifluoromethoxyphenyl)boronic Acid CAS 345226-20-2
| CAS No. | 345226-20-2 |
| Molecular Formula | C7H5BClF3O3 |
| Molecular Weight | 240.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2-Chloro-4-trifluoromethoxyphenyl)boronic Acid (CAS 345226-20-2) is a high-purity analytical reference standard with the molecular formula C7H5BClF3O3 and a molecular weight of 240.37 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (2-Chloro-4-trifluoromethoxyphenyl)boronic Acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 240.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), (2-Chloro-4-trifluoromethoxyphenyl)boronic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BClF3O3 |
| Molecular Weight | 240.37 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-5-(trifluoromethoxy)phenylboronic Acid (CAS 1022922-16-2)
- (4-Chloro-2-(trifluoromethoxy)phenyl)boronic acid (CAS 1095990-65-0)
- (3-Chloro-5-(trifluoromethoxy)phenyl)boronic acid (CAS 1451393-40-0)
- 3-Chloro-2-(trifluoromethoxy)phenylboronic acid (CAS 1942072-67-4)
- (3-Chloro-4-(trifluoromethoxy)phenyl)boronic acid (CAS 870822-79-0)
- [5-Chloro-2-(trifluoromethoxy)phenyl]boronic acid (CAS 870822-78-9)
- 2-Chloro-6-(trifluoromethoxy)phenylboronic acid (CAS 2036084-49-6)
- 3-Chloro-2-hydroxy-4-(trifluoromethyl)phenylboronic acid (CAS 2121512-08-9)
Recommended Standards
- (S)-2-Amino-N-isopropyl-N-((3-methylthiophen-2-yl)methyl)propanamide (CAS 1354009-18-9)
- 1,5,6,7-Tetrahydro-2H-cyclopenta[4,5]thieno[2,3-d]pyrimidine-2,4(3H)-dithione (CAS 351005-64-6)
- N1-Isopropyl-N1-((3-(methylthio)pyrazin-2-yl)methyl)ethane-1,2-diamine (CAS 1353980-48-9)
- 2-(Isopentylthio)-6-propylpyrimidin-4(1H)-one (CAS 62459-10-3)
- 5-Cyclopropoxy-N1,N1,N3-trimethylisophthalamide (CAS 1243348-08-4)
- Ethyl 1,4-diazepane-2-carboxylate (CAS 850786-98-0)
- 2-Bromo-5-hydroxynicotinonitrile (CAS 1805597-66-3)
- Methyl 4-bromo-6-nitroquinoline-2-carboxylate (CAS 1363017-31-5)
- 2-(6-Methylpyridazin-3-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine (CAS 949962-95-2)
- 6-(4-Fluorophenoxy)-4-methylpyridin-3-amine (CAS 753921-02-7)
- Benzyl 3-(aminomethyl)azetidine-1-carboxylate hydrochloride (CAS 1203086-10-5)
- Methyl 2-bromo-5-cyano-4-formylbenzoate (CAS 1804381-26-7)
- 5-Chloro-2-methylquinolin-8-ol (CAS 24263-93-2)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com