2-Chloro-6-fluoro-3-methoxyphenylboronic acid pinacol ester CAS 2121512-16-9
| CAS No. | 2121512-16-9 |
| Molecular Formula | C13H17BClFO3 |
| Molecular Weight | 286.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-6-fluoro-3-methoxyphenylboronic acid pinacol ester.
CATO supplies 2-Chloro-6-fluoro-3-methoxyphenylboronic acid pinacol ester (CAS 2121512-16-9), a certified reference material (molecular formula C13H17BClFO3, MW 286.53 g/mol) for analytical method development and quality control.
Based on its molecular formula C13H17BClFO3, 2-Chloro-6-fluoro-3-methoxyphenylboronic acid pinacol ester contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 286.53 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-6-fluoro-3-methoxyphenylboronic acid pinacol ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H17BClFO3 |
| Molecular Weight | 286.53 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-(4-Chloro-5-fluoro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1092581-00-4)
- 2-(4-Chloro-2-fluoro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1126321-06-9)
- 2-(3-Chloro-5-fluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1422022-15-8)
- 4-Chloro-3-fluoro-2-methoxyphenylboronic acid pinacol ester (CAS 1628524-83-3)
- 2-(6-Chloro-2-fluoro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1628684-12-7)
- (2-Chloro-4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol (CAS 2068789-77-3)
- 2-(2-Chloro-5-fluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2445647-03-8)
- 2-(3-Chloro-2-fluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121512-36-3)
Recommended Standards
- 2-(3-Chloro-5-fluoro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121514-87-0)
- 2-Fluoro-4-methoxybenzeneboronic acid pinacol ester, 97% (CAS 628692-21-7)
- 3-Chloro-6-fluoro-2-methoxyphenylboronic acid pinacol ester (CAS 2121513-63-9)
- 5-Chloro-2-fluoro-4-methoxyphenylboronic acid pinacol ester (CAS 2121513-64-0)
- 2-Amino-N-(2,2,2-trifluoroethyl)propanamide (CAS 934214-44-5)
- (S)-tert-Butyl 2-amino-2-cyclohexylacetate (CAS 688735-01-5)
- 6-Amino-7H-purin-8-ol (CAS 21149-26-8)
- 2-Bromo-6-cyanoisonicotinic acid (CAS 1393569-72-6)
- Tributyltetradecylphosphonium chloride (CAS 81741-28-8)
- 4-(Hydroxymethyl)thiazole (CAS 7036-04-6)
- (1S,2R)-2-(1-methyl-1H-pyrazol-5-yl)cyclohexan-1-ol (CAS 1450595-87-5)
- Ethyl 2-(1-bromoethyl)-5-methoxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylate (CAS 2857080-72-7)
- 2-(2-Piperidinyl)ethyl propyl ether hydrochloride (CAS 1185297-65-7)
- Fibrinogen Related Peptide (CAS 80755-86-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com