Losartan Impurity 55 CAS 212316-86-4
| CAS No. | 212316-86-4 |
| Molecular Formula | C44H44Cl2N12O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Losartan Impurity 55 (CAS 212316-86-4), a pharmacopoeial impurity reference standard (molecular formula C44H44Cl2N12OK, MW 866.92 g/mol) used for the identification and quantification of trace impurities in APIs.
Losartan Impurity 55 (C44H44Cl2N12OK) contains a salt form, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Losartan Impurity 55 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C44H44Cl2N12O K |
| Molecular Weight | 866.92 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 28.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2017 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 12 |
Related Losartan Standards
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- 5-{[(2-Piperazin-1-ylethyl)amino]methylene}pyrimidine-2,4,6(1H,3H,5H)-trione (CAS 299442-86-7)
- (1S,3r,5R)-spiro[bicyclo[3.3.1]nonane-3,2’-oxirane]-7-one (CAS 53110-08-0)
- 1-Isopropyl-7-methyl-1H-benzo[d][1,2,3]triazole (CAS 169212-63-9)
- (S)-Oxiran-2-ylmethyl 4-nitrobenzenesulfonate (CAS 118712-60-0)
- Iohexol Impurity N9 (CAS 122731-58-2)
- 2-(3,5-Dichlorophenoxy)-N,N,N-trimethylethan-1-aminium iodide (CAS 1025707-89-4)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com