Losartan EP Impurity I CAS 1006062-28-7
| CAS No. | 1006062-28-7 |
| Molecular Formula | C41H37ClN6O |
| Molecular Weight | 665.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Losartan EP Impurity I is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 665.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Losartan EP Impurity I (CAS 1006062-28-7), a pharmacopoeial impurity reference standard (molecular formula C41H37ClN6O, MW 665.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Losartan EP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C41H37ClN6O |
| Molecular Weight | 665.23 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 26.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Losartan Standards
- Losartan EP Impurity H (CAS 133909-99-6)
- Losartan Impurity N13 (CAS 133727-10-3)
- Losartan Impurity N3 (CAS 133910-00-6)
- Losartan impurity 32 (CAS CATO-C4X-168332)
- Losartan Impurity 27 (CAS CATO-C4X-168327)
- Losartan N1-Glucuronide (CAS 138584-34-6)
- Losartan N2-Glucuronide (CAS 138584-35-7)
- Losartan Impurity 52 (CAS CATO-C4X-168352)
Recommended Standards
- N-Trithyl Losartan (CAS 124751-00-4)
- N-Trityl Losartan Isomer (CAS 150098-04-7)
- Balanophorin B (CAS 32214-80-5)
- (3-((Triisopropylsilyl)ethynyl)-4-((trimethylsilyl)ethynyl)-hexa-3-en-1,5-diyne-1,6-diyl)bis(triisopropylsilane) (CAS 142761-77-1)
- Progesterone Impurity 75 (CAS 796-24-7)
- Aztreonam impurity 69 (CAS CATO-C4X-152269)
- Dequalinium Impurity 10 (CAS CATO-C4X-193610)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com