Linagliptin-d4 CAS 2140263-92-7
| CAS No. | 2140263-92-7 |
| Molecular Formula | - |
| Molecular Weight | 476.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Linagliptin-d4 is closely related to deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Linagliptin-d4 (CAS 2140263-92-7), a certified reference material (molecular formula C25H24D4N8O2, MW 476.57 g/mol) for analytical method development and quality control.
Structurally, Linagliptin-d4 (C25H24D4N8O2) contains deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 476.57 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H24D4N8O2 |
| Molecular Weight | 476.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 8 |
Related Linagliptin Standards
- Linagliptin-13C-d3 (CAS 1398044-43-3)
- Linagliptin D3 (CAS 1398044-48-8)
- Linagliptin impurity 128 (CAS CATO-C4X-1101128)
- Linagliptin Metabolite CD1790 (CAS 1620278-39-8)
- Linagliptin Impurity 113 (CAS 2803369-89-1)
- Linagliptin (CAS 668270-12-0)
- Linagliptin Impurity 122 (CAS 2446799-72-8)
- Linagliptin impurity 137 (CAS CATO-C4X-1101137)
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