Betamethasone Cyclic 17,21-(Ethyl Orthopropionate) CAS 1062-09-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Betamethasone Cyclic 17,21-(Ethyl Orthopropionate).

Betamethasone Cyclic 17,21-(Ethyl Orthopropionate) (CAS 1062-09-5), molecular formula C27H37FO6 and molecular weight 476.58 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Betamethasone Cyclic 17,21-(Ethyl Orthopropionate) (C27H37FO6) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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