Brexpiprazole Impurity 35 CAS 2143944-65-2
| CAS No. | 2143944-65-2 |
| Molecular Formula | C16H21N2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Brexpiprazole Impurity 35 (CAS 2143944-65-2, C16H21N2SBr) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Brexpiprazole Impurity 35 (C16H21N2SBr) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Brexpiprazole Impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H21N2S Br |
| Molecular Weight | 353.32 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Brexpiprazole Standards
- Brexpiprazole Impurity 53 (CAS 102-92-1)
- Brexpiprazole Impurity 41 (CAS 105684-85-3)
- Brexpiprazole Impurity 113 (CAS 105685-06-1)
- Brexpiprazole Impurity 28 (CAS 1191900-51-2)
- Brexpiprazole Impurity 10 (CAS 1191900-58-9)
- Brexpiprazole Impurity 56 (CAS 1191900-59-0)
- Brexpiprazole Impurity 133 (CAS 1268367-99-2)
- Brexpiprazole impurity 114 (CAS 131540-81-3)
Recommended Standards
- Minoxidil EP Impurity D (CAS 75105-16-7)
- Methylene blue /Methylthioninium Chloride Impurity 28 (CAS CATO-C4X-189628)
- Azilsartan Impurity 134 (CAS 57113-88-9)
- N-(4-fluorobenzyl)-2,2,6,6-tetramethylpiperidin-4-amine (CAS 626212-92-8)
- 2-Fluoro-4-(hydroxymethyl)benzonitrile (CAS 222978-02-1)
- (R)-2-(4-bromo-3-methylphenyl)pyrrolidine (CAS 1213683-87-4)
- Ketoprofen 1,4-Sorbitol Ester (CAS CATO-C4X-147118)
- 1,1,2,2-Tetrakis(3'-([2,2':6',2''-terpyridin]-4'-yl)-[1,1'-biphenyl]-3-yl)ethene (CAS 2467796-31-1)
- 3-Cyclohexyl-N-(4-hydroxybutan-2-yl)propanamide (CAS 1424475-55-7)
- (Des-Thr7)-Glucagon trifluoroacetate salt (CAS 1802078-28-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com