Apremilast Impurity 38 CAS 2095036-40-9
| CAS No. | 2095036-40-9 |
| Molecular Formula | C20H20N2O8S |
| Molecular Weight | 448.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Apremilast Impurity 38 (CAS 2095036-40-9), a pharmacopoeial impurity reference standard (molecular formula C20H20N2O8S, MW 448.45 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Apremilast Impurity 38 (C20H20N2O8S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H20N2O8S |
| Molecular Weight | 448.45 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity 36 (CAS 253168-82-0)
- Apremilast Impurity 52 (CAS CATO-C4X-100952)
- Apremilast impurity 15 (CAS 1384441-38-6)
- Apremilast Impurity 23 (CAS 2077897-94-8)
- Apremilast Impurity 45 (CAS CATO-C4X-100945)
- Apremilast Impurity 75 (CAS CATO-C4X-100975)
- Apremilast impurity 8 (CAS CATO-C4X-10098)
- Apremilast Impurity 78 (CAS CATO-C4X-100978)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com