Cholic Acid Impurity 72 CAS 25480-14-2
| CAS No. | 25480-14-2 |
| Molecular Formula | C25H38O5 |
| Molecular Weight | 418.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cholic Acid Impurity 72.
As a process- or degradation-related impurity, Cholic Acid Impurity 72 (CAS 25480-14-2, C25H38O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cholic Acid Impurity 72 (C25H38O5) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cholic Acid Impurity 72 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H38O5 |
| Molecular Weight | 418.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
Related Cholic Standards
- Cholic Acid Impurity N77 (CAS 14772-99-7)
- Cholic Acid Impurity 39 (CAS CATO-C4X-116039)
- Cholic Acid Impurity 69 (CAS 105660-11-5)
- Cholic Acid Impurity 4 (CAS CATO-C4X-11604)
- Cholic Acid Impurity 1 (CAS 1448-36-8)
- Cholic Acid Impurity 59 (CAS 10190-22-4)
- Cholic-2,2,4,4-d4 Acid (CAS 116380-66-6)
- Cholic Acid-24-13C (CAS 52886-36-9)
Recommended Standards
- 17-Hydroxy-pregn-5-ene-3,20-dione Cyclic Bis(1,2-ethanediyl Acetal) 17|A-Hydroxypregn-5-ene-3,20-dione-3,20-bis(ethyleneketal) 3386-00-3 (CAS 3386-00-3)
- Cinnarizine EP Impurity E (CAS 216581-01-0)
- Oxazole, 2,2′-methylenebis[4-[4-(1,1-dimethylethyl)phenyl]-4,5-dihydro-, (4R,4′R)- (CAS 866540-34-3)
- 2-Nor Latanoprost (CAS CATO-C4X-19414)
- Ubidecarenone impurity 19 (CAS 5677-54-3)
- Pemafibrate Impurity 70 (CAS CATO-C4X-290370)
- Vericiguat Impurity 67 (CAS 2755814-39-0)
- n1,n1,2,2-Tetramethyl-n3-(thiophen-2-ylmethyl)propane-1,3-diamine (CAS 1019504-60-9)
- 2-(2-Bromo-4-methylphenoxy)ethan-1-amine hydrochloride (CAS 474370-89-3)
- 4,7-Dihydroxy-3-(2-methoxyphenyl)-2H-chromen-2-one (CAS 21229-16-3)
- 2-(4-Fluoro-2-methylphenyl)acetic acid, 97% (CAS 407640-40-8)
- 2-Phenyl-1,7-naphthyridine-4-carboxylic acid (CAS 855521-66-3)
- 2-(Chloromethyl)-1-fluoro-4-(trifluoromethoxy)benzene (CAS 1517586-69-4)
- D-Pro36-Tirzepatide (CAS CATO-CPTD788903)
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